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KMID : 0358519940060010113
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Korean Journal of Occupational and Environmental Medicine
1994 Volume.6 No. 1 p.113 ~ p.121
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Styrene in Air and Blood and Mandelic Acid in Urine in the Workers Exposed to Styrene
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정호근
강성규/양정선/김기웅/이종성/조영숙/박인정.
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Abstract
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The concentration of styrene in air and in blood and mandelic acid in urine were checked for the 60 workers with normal liver function, exposed to styrene. Styrene in air were sampled with personal air sampler at least 4 hours and analyzed by gas
chromatography. Blood and spot urine were collected at the end of shift with a vacuum tube and a polyethylene bottle and analyzed by gas chromatography and high performance liquid chromatography. Means of air and blood styrene and urine mandelic
acid
were 8.16 ppm(geometric mean), 0.199 mg/L, and 0.519 g/g creatinine, respectively. The concentration of styrene in air and mandelic acid in urine were high in the FRP factories and low in polymerization factory, Styrene in blood showed large
difference
by the working process, Styrene in air showed a good correlation with mandelic acid in urine(r=0.6369) and styrene in blood(r=0.6371). The mandelic acid in urine and styrene in blood corresponded to exposure of 50 ppm styrene were 0.890g/g
creatinine
and 0.434 mg/L. However, hippuric acid in urine did not show any correlation with styrene in air. Urine mandelic acid excretion expected ratio showed a tendency to decrease according to obesity index and to increase with alcohol consumption
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KEYWORD
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